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Glossary - Lipids

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Lipids

Lipids: Another word for "fats", are an important part of living cells. Together with carbohydrates and proteins, lipids are the main constituents of plant and animal cells. Cholesterol - Cholesterol is a substance (a steroid) that is essential for life. It forms the membranes for cells in all organs and tissues in your body. It is used to make hormones that are essential for development, growth and reproduction. It forms bile acids that are needed to absorb nutrients from food. A small amount of your body's cholesterol circulates in the blood in complex particles called lipoproteins. These lipoproteins include some particles that carry excess cholesterol away for disposal (see HDL, good cholesterol) and some particles that deposit cholesterol in tissues and organs (see LDL, bad cholesterol). Cholesterol levels fluctuate over time. The measured cholesterol level may differ by as much as 10% from one month to another. It may go up sometimes or it may go down sometimes. These changes are called biological variation and they represent normal variability inherent in human metabolism. High cholesterol may be the result of an inherited disease or it may result from a diet high in saturated fats. For many people it is caused by a combination of both a high fat diet and an inherited tendency towards high cholesterol. All adults over the age of 20 should have a cholesterol test at least once every five years. HDL cholesterol - One of the classes of lipoproteins that carry cholesterol in the blood. HDL is considered to be beneficial because it removes excess cholesterol and disposes of it. Hence HDL cholesterol is often termed "good" cholesterol.

 

LDL cholesterol - A type of lipoprotein that carries cholesterol in the blood. LDL is considered to be undesirable because it deposits excess cholesterol in walls of blood vessel and contributes to "hardening of the arteries" and heart disease. Hence LDL cholesterol is often termed "bad" cholesterol. The test for LDL measures the amount of LDL cholesterol in blood.

Triglycerides - The body's storage form for fat. Most triglycerides are found in adipose (fat) tissue. Some triglycerides circulate in the blood to provide fuel for muscles to work. Extra triglycerides are found in the blood after eating a meal-when fat is being sent from the gut to adipose tissue for storage

Very Low Density Lipoprotein (VLDL) - One of three major "lipid packets," which also include high density lipoprotein (HDL) and low density lipoprotein (LDL). Each one of these "packets" contains triglyceride and cholesterol, but in varying amounts unique to each packet. LDL contains mainly cholesterol, while HDL contains mostly the excess cholesterol removed from tissues and carried back to the liver, and VLDL contains mainly triglyceride. It contains so much triglyceride, in fact, that you can get an idea of what the VLDL concentration is by dividing the triglyceride value by 5. At present, there is no direct way of measuring VLDL, so the direct measurement of triglyceride is considered the next best thing, and the calculation is done if needed.